TAKAITACCE DA BAYANIN GWAJI
M.pneumoniae na iya haifar da yawan bayyanar cututtuka kamar su ciwon huhu na farko, tracheobronchitis, da kuma cututtuka na numfashi na sama.Tracheobronchitis ya fi zama ruwan dare a cikin yara masu raguwar tsarin rigakafi, kuma har zuwa kashi 18% na yaran da suka kamu da cutar suna buƙatar asibiti.A asibiti, M. pneumoniae ba za a iya bambanta da ciwon huhu da wasu kwayoyin cuta ko ƙwayoyin cuta ke haifar da su.Takamaiman ganewar asali yana da mahimmanci saboda maganin kamuwa da cutar M. pneumoniae tare da maganin rigakafi na β-lactam ba shi da tasiri yayin da magani tare da macrolides ko tetracyclines na iya rage tsawon lokacin rashin lafiya.
Rikon M. pneumoniae zuwa epithelium na numfashi shine mataki na farko a cikin tsarin kamuwa da cuta.Wannan tsarin haɗin kai wani abu ne mai rikitarwa wanda ke buƙatar sunadaran adhesin da yawa, kamar P1, P30, da P116.Gaskiyar abin da ya faru na M. pneumoniae kamuwa da cuta ba a bayyane yake ba saboda yana da wuyar ganewa a farkon matakan kamuwa da cuta.
KA'IDA
Mycoplasma Pneumoniae IgG/IgM Kit ɗin Gwajin gaggawa bisa ka'idar gwajin gwaji mai inganci don tantance Mycoplasma Pneumoniae IgG/IgM antibody a cikin jini na ɗan adam, plasma ko duka jini.StripA ya ƙunshi: 1) wani burgundy mai launi conjugate conjugate da MPgaid conjugate pad (antigen conjugate pad). wani nitrocellulose membrane tsiri dauke da wani gwajin band (T band) da kuma kula da band (C band).An riga an yi wa rukunin T ɗin riga da linzamin kwamfuta anti-human IgG antibody, kuma rukunin C an riga an yi masa rufi da goat anti-mouse IgG antibody.Strip B ya ƙunshi : 1) kushin conjugate mai launin burgundy mai ɗauke da MP antigen da aka haɗa tare da zinari na colloid (MP Antigen conjugates), 2) wani tsiri na nitrocellulose mai ɗauke da band ɗin gwaji (T band) da kuma bandeji mai sarrafawa (C band).An riga an yi wa rukunin T ɗin riga da linzamin kwamfuta anti-human IgM antibody, kuma rukunin C an riga an riga an yi masa rufi da goat anti-mouse IgG antibody.
Strip A: Lokacin da aka ba da isasshen adadin samfurin gwaji a cikin rijiyar samfurin kaset ɗin gwajin, samfurin yana ƙaura ta hanyar aikin capillary a cikin kaset. MP IgG antibody idan akwai a cikin samfurin zai ɗaure zuwa MP Antigen conjugates.Immunocomplex an kama shi a jikin membrane ta riga-kafin Mouse anti-human IgG antibody, yana samar da rukunin T mai launin burgundy, yana nuna sakamako mai kyau na MP IgG.Rashin rukunin T yana nuna sakamako mara kyau.Gwajin ya ƙunshi iko na ciki (C band) wanda ya kamata ya nuna band mai launin burgundy na immunocomplex na goat anti-mouse IgG/ linzamin kwamfuta IgG-gold conjugate ko da kuwa kasancewar T band mai launi.In ba haka ba, sakamakon gwajin ba shi da inganci kuma dole ne a sake gwada samfurin da wata na'ura.
Strip B: Lokacin da aka ba da isasshen adadin samfurin gwajin a cikin rijiyar samfurin kaset ɗin gwajin, samfurin yana ƙaura ta hanyar aikin capillary a cikin kaset. MP IgM antibody idan akwai a cikin samfurin zai ɗaure zuwa MP Antigen conjugates.Immunocomplex an kama shi a jikin membrane ta riga-kafin Mouse anti-human IgM antibody, yana samar da rukunin T mai launin burgundy, yana nuna sakamako mai kyau na MP IgM.Rashin rukunin T yana nuna sakamako mara kyau.Gwajin ya ƙunshi iko na ciki (C band) wanda ya kamata ya nuna band mai launin burgundy na immunocomplex na goat anti-mouse IgG/ linzamin kwamfuta IgG-gold conjugate ko da kuwa kasancewar T band mai launi.In ba haka ba, sakamakon gwajin ba shi da inganci kuma dole ne a sake gwada samfurin da wata na'ura.
